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8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cAMPS ), sodium salt

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8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cAMPS ), sodium salt

品牌：Biolog Life Science

貨號：B 001-05

規(guī)格：B 001-05

貨期：Biolog Life Science Institute

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品牌：Biolog Life Science Institute 貨號：B 001-05 品名：Rp-8-Br-cAMPS

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Rp-8-Br-cAMPS

8- Bromoadenosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer ( Rp-8-Br-cAMPS ), sodium salt

Lipophilic analogue of the cyclic AMP antagonist Rp-cAMPS

Cat. No.: B 001

CAS No.: [129735-00-8]

Cat. No.: B 001-05
Unit: 5 μmol / ~2.2 mg

Cat. No.	B 001
CAS number	[129735-00-8]
Purity	> 99% HPLC
Salt form	Sodium
Storage temperature	-20°C / -4°F
Molecular formula	C??H??BrN?O?PS · Na
Molecular weight [g/mol]	446.2
cAMP modified at the exocyclic oxygen	equatorial (Rp-)
Modifications	8-cAMP
Target	PKA (cAK) Inhibitor
Lipophilicity	1.47
Absorption max [nm]	264
Molar extinction coefficient ε [L·mol?1·cm?1]	17000

DESCRIPTION:
For other salt forms please inquire. Lipophilic analogue of the cyclic AMP antagonist Rp-cAMPS. Prefers type I of protein kinase A. Resistant against mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane-permeant compared to Rp-cAMPS (Cat. No. A 002) or 8-Br-cAMP (Cat. No. B 007). Detailed technical information and updated reference list available on request. References: Gjertsen et al., J. Biol. Chem., 270, 20599 - 20607 (1995), Aandahl et al., FASEB J., 12, 855 - 863 (1998)