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Product Description
Clone: FG1/8
Isotype: IgG1
Tested Applications: FCM
Conjugated: PE
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Immunogen: T cells from leukemic HPB-ALL
Species Reactivity: Human
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Recommended Usage: CD98, clone FG1/8, is a mAb intended for the identification of human leukocyte lineages. This reagent is effective for direct IFstaining of human tissue for FCM analysis using ≤1 μg/106 cells.
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Large description: This antibody reacts with the CD98 antigen, which is broadly expressed on peripheral blood lymphocytes, monocytes and granulocytes (low) .It is also expressed on non-hematopoietic cells. Reports suggest that CD98 may be involved in the regulation of cellular activation. CD98 is up-regulated on leukocytes and in inflammatory lesions, and strongly expressed by neoplastic cells. However, expression is not hematopoietic specific. CD98 is expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. Also it is expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas, in retinal endothelial cells and in the intestinal epithelial cell line C2BBe1.
Other names: 4F2, FRP-1, RL-388, 4F2hc, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2