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Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody

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Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody

品牌：Abmgood

貨號：Y105238

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Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody

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Overview	Print Version
Product Name	Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody
Description	Rabbit polyclonal to VEGF Receptor 2. VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as s for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Subtype	polyclonal
Application	IHC
Raised In	Rabbit
Immunogen	Synthetic peptide - KLH conjugated
Guarantee	abm guarantees that all our Anti-Vascular Endothelial Growth Factor Receptor 2 (KDR), Human Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Properties
Formulation	Liquid
Quantity	50 μg
Clone	Polyclonal Antibody
Storage	This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Purity	Affinity purified
Species Reactivity	Human
Specific References
Y105238 has not yet been referenced specifically in any publications.