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Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody
品牌：Antibodies
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規(guī)格：50μl
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Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody
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Name: Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody
See all Ephrin B1 primary antibodies
Description: Rabbit polyclonal antibody to Ephrin B1 / B2 / B3 (Phospho-Tyr324)
Specificity: The antibody detects endogenous levels of Ephrin B1 / B2 / B3 only when phosphorylated at tyrosine 324.
Applications: WB, IHC
Dilutions: Western blotting: 1:500~1:1000Immunohistochemistry: 1:50~1:100
Reactivity: Human
Immunogen: Peptide sequence around phosphorylation site of tyrosine 324 (G-D-Y(p)-G-H) derived from Human Ephrin B1 / B2 / B3 .
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20?C / 1 year
Function: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Tissue Specificity: Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
Involvement in Disease: Craniofrontonasal syndrome: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies.
Sequence Similarities: Belongs to the ephrin family.
Post-Translational Modification: Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 1947?Human
  • Omim: 300035?Human
  • SwissProt: P98172?Human
  • Unigene: 144700?Human
    		•
    Synonyms:
  • CFND Antibody
  • CFNS Antibody
  • Craniofrontonasal syndrome (craniofrontonasal dysplasia) Antibody
  • EFL 3 Antibody
  • EFL-3 Antibody
  • EFL3 Antibody
  • EFNB1 Antibody
  • EFNB1_HUMAN Antibody
  • Elk L Antibody
  • ELK ligand Antibody
  • ELK-L Antibody
  • Eph related receptor tyrosine kinase ligand 2 Antibody
  • EPH-related receptor tyrosine kinase ligand 2 Antibody
  • Ephrin B1 Antibody
  • Ephrin-B1 Antibody
  • EPLG2 Antibody
  • LERK 2 Antibody
  • LERK-2 Antibody
  • LERK2 Antibody
  • Ligand of eph related kinase 2 Antibody
  • MGC8782 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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