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Anti-DOK3 Antibody
品牌：Antibodies
貨號：
規(guī)格：50μl
貨期：
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Anti-DOK3 Antibody
商品詳情 參考文獻 相關(guān)資料
Name: Anti-DOK3 Antibody
See all DOK3 primary antibodies
Description: Rabbit polyclonal antibody to DOK3
Specificity: The antibody detects endogenous level of total DOK3 protein.
Applications: E, WB, IHC
Dilutions: ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:10-1:50
Reactivity: Human
Immunogen: Fusion protein corresponding to C terminal 300 amino acids of human docking protein 3
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Predicted MW: 53kd
Formulation: Supplied at 1mg / mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Storage: Store at -20?C / 1 year
Function: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity).
Tissue Specificity: Expressed in spleen.
Sequence Similarities: Belongs to the DOK family. Type A subfamily.
Post-Translational Modification: Constitutively tyrosine-phosphorylated.
Cellular Location: Cytoplasm. Cell membrane.
Database Links:
  • Entrez Gene: 79930?Human
  • Omim: 611435?Human
  • SwissProt: Q7L591?Human
  • Unigene: 720849?Human
    		•
    Synonyms:
  • Docking protein 3 Antibody
  • DOK 3 Antibody
  • DOK Like Protein Antibody
  • DOK3 Antibody
  • DOK3_HUMAN Antibody
  • DOKL Pending Antibody
  • Downstream of tyrosine kinase 3 Antibody
  • p62 DOK Like Protein Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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