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Anti-CXCR-3 Antibody
品牌：Antibodies
貨號：
規(guī)格：50μl
貨期：

Anti-CXCR-3 Antibody
商品詳情 參考文獻 相關資料
Name: Anti-CXCR-3 Antibody
See all CXCR-3 primary antibodies
Description: Rabbit polyclonal antibody to CXCR-3
Specificity: CXCR-3 pAb detects endogenous levels of CXCR-3 protein.
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length Human CXCR-3.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 40 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1mg/ml in PBS?with?0.1%?Sodium?Azide,?50%?Glycerol.
Function: Isoform 1: Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway (PubMed:12782716). Binds to CCL21. Probably promotes cell chemotaxis response.
Tissue Specificity: Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level).
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.
Post-Translational Modification: Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding and subsequent signal transduction induction.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 2833?Human
  • Entrez Gene: 12766?Mouse
  • Entrez Gene: 84475?Rat
  • Omim: 300574?Human
  • SwissProt: P49682?Human
  • SwissProt: O88410?Mouse
  • SwissProt: Q9JII9?Rat
  • Unigene: 198252?Human
  • Unigene: 12876?Mouse
  • Unigene: 24787?Rat
    		•
    Synonyms:
  • C-X-C chemokine receptor type 3 Antibody
  • CD 183 Antibody
  • CD182 Antibody
  • CD183 Antibody
  • Chemokine (C X C motif) receptor 3 Antibody
  • Chemokine (C X C) receptor 3 Antibody
  • Chemokine CXC Motif Receptor 3 Antibody
  • CKR L2 Antibody
  • CKR-L2 Antibody
  • CKRL2 Antibody
  • CMKAR3 Antibody
  • CXC-R3 Antibody
  • CXCR-3 Antibody
  • CXCR3 Antibody
  • CXCR3_HUMAN Antibody
  • G Protein Coupled Receptor 9 Antibody
  • G protein-coupled receptor 9 Antibody
  • GPR9 Antibody
  • Interferon-inducible protein 10 receptor Antibody
  • IP-10 receptor Antibody
  • IP10 Antibody
  • IP10 R Antibody
  • IP10 receptor Antibody
  • IP10-R Antibody
  • IP10R Antibody
  • Mig R Antibody
  • Mig receptor Antibody
  • Mig-R Antibody
  • MIGR Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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