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Anti-PTBP1 Antibody

品牌：Antibodies

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規(guī)格：100μg

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Anti-PTBP1 Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-PTBP1 Antibody See all PTBP1 primary antibodies
Description:	Goat polyclonal antibody to PTBP1.
Applications:	ELISA, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide corresponding to Human PTBP1 (N terminal).
Sequence:	DGIVPDIAVGTKR-C
Host:	Goat
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Unconjugated
Purification:	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration:	100 μg at 0.5 mg/ml.
Product Form:	Liquid
Formulation:	Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage:	Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Target

Function:	Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (By similarity).
Cellular Location:	Nucleus.
Database Links:	Entrez Gene: 5725?Human Entrez Gene: 19205?Mouse Entrez Gene: 29497?Rat Omim: 600693?Human SwissProt: P26599?Human SwissProt: P17225?Mouse SwissProt: Q00438?Rat Unigene: 172550?Human Unigene: 265610?Mouse Unigene: 472059?Mouse Unigene: 64440?Rat
Synonyms:	57 kDa RNA binding protein PPTB 1 Antibody 57 kDa RNA-binding protein PPTB-1 Antibody Heterogeneous nuclear ribonucleoprotein I Antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I Antibody hnRNP I Antibody HNRNP-I Antibody HNRNPI Antibody HNRPI Antibody MGC10830 Antibody MGC8461 Antibody Polypyrimidine tract binding protein Antibody Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) Antibody Polypyrimidine Tract Binding Protein 1 Antibody Polypyrimidine tract-binding protein 1 Antibody pPTB Antibody PTB Antibody PTB 1 Antibody PTB 2 Antibody PTB 3 Antibody PTB 4 Antibody PTB T Antibody PTB1 Antibody PTB2 Antibody PTB3 Antibody PTB4 Antibody PTBP 1 Antibody PTBP1 Antibody PTBP1_HUMAN Antibody PTBT Antibody RNA Binding Protein Antibody
Information:	Target information shown above is from the UniProt Consortium.