亚洲欧洲自拍拍偷午夜色无码,亚洲精品无码aⅴ中文字幕蜜桃,亚洲欧美日韩成人一区二区三区

您好，歡迎來到拜力生物網(wǎng)站！請登錄注冊

我的訂單 | 聯(lián)系我們 | 在線客服QQ：3012681483 | 客服電話：400-968-7988 | 工作時間：08:30-17:30

主營產(chǎn)品： ELISA試劑盒、抗體、補體血清、兔補體、干擾素、小鼠測溫儀、進口試劑、Quidel代理、Swant代理、PBL Assay Science代理

所在位置：首頁 > 產(chǎn)品中心 > Antibodies > Antibodies產(chǎn)品

訂購信息

上海拜力生物科技公司

Tel:400-968-7988 021-33779008

Anti-Caspase 3 (D146) Antibody

品牌：Antibodies

貨號：

規(guī)格：50μl

貨期：

立即購買加入購物車

Anti-Caspase 3 (D146) Antibody

商品詳情參考文獻相關(guān)資料

Name:	Anti-Caspase 3 (D146) Antibody See all Caspase 3 primary antibodies
Description:	Rabbit polyclonal antibody to Caspase 3 (D146)
Specificity:	Caspase 3 (D146) pAb detects endogenous levels of Caspase 3 protein.
Applications:	WB, IHC, IF
Reactivity:	Human, Mouse, Rat
Immunogen:	Synthetic peptide, corresponding to amino acids 120-170 of Human Caspase 3.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Molecular Weight:	~ 35 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form:	1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Function:	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Tissue Specificity:	Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Sequence Similarities:	Belongs to the peptidase C14A family.
Post-Translational Modification:	Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the propeptides is likely due to the autocatalytic activity of the activated protease. Active heterodimers between the small subunit of caspase-7 protease and the large subunit of caspase-3 also occur and vice versa.
Cellular Location:	Cytoplasm.
Synonyms:	CASP3 Antibody Caspase 3 Antibody CPP32 Antibody LICE Antibody SCA1 Antibody SREBP cleavage activity 1 Antibody Yama protein Antibody
Information:	Target information shown above is from the UniProt Consortium.